Electrical Stimulation Depresses Epileptiform Activity
نویسندگان
چکیده
منابع مشابه
Local suppression of epileptiform activity by electrical stimulation in rat hippocampus in vitro.
High frequency electrical stimulation of deep brain structures (DBS) has been effective at controlling abnormal neuronal activity in Parkinson's patients and is now being applied for the treatment of pharmacologically intractable epilepsy. The mechanisms underlying the therapeutic effects of DBS are unknown. In particular, the effect of the electrical stimulation on neuronal firing remains poor...
متن کاملSuppression and Control of Epileptiform Activity by Electrical Stimulation: A Review
Epilepsy is a devastating disease affecting 1% of the world’s population. Although drug therapy is effective in many patients, 25% are not responsive to anticonvulsants. In addition, up to 50% of those receiving regular medication suffer major side effects. Surgical resection is another treatment also associated with serious complications. An alternative method to control seizure activity is el...
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SARNA, S. K., AND E. E. DANIEL. Electrical stimulation of gastric electrical control activity. Am. J. Physiol. 225(l): 125-131. 1973.Gastric electrical control activity in anesthetized dogs was stimulated by voltage pulses of 100 msec duration and lto 25-v amplitude. The gastric control waves could be entrained from any site in the electrically active region on the anterior and posterior sides....
متن کاملBombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex.
Bombesin and the bombesin-like peptides including neuromedin B (NMB) and gastrin-releasing peptide (GRP) are important neuromodulators in the brain. We studied their effects on GABAergic transmission and epileptiform activity in the entorhinal cortex (EC). Bath application of bombesin concentration-dependently increased both the frequency and amplitude of sIPSCs recorded from the principal neur...
متن کاملIn vivo neuronal firing patterns during human epileptiform discharges replicated by electrical stimulation
OBJECTIVE To describe neuronal firing patterns observed during human spontaneous interictal epileptiform discharges (IEDs) and responses to single pulse electrical stimulation (SPES). METHODS Activity of single neurons was recorded during IEDs and after SPES in 11 consecutive patients assessed with depth EEG electrodes and attached microelectrodes. RESULTS A total of 66 neurons were recorde...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2003
ISSN: 1535-7597,1535-7511
DOI: 10.1046/j.1535-7597.2003.03410.x